Author/Authors :
Abdulla, Manal Medhat University of Baghdad - College of Science - Department of Physics, Iraq , AI-Ani, Fakhir University of Baghdad - College of Science - Department of Physics, Iraq , AL-Ani, Abd AI-Satar University of Baghdad - College of Science - Department of Physics, Iraq
Abstract :
Objective: Using a modified laser light scattering tech nique to study the red blood cells aggregation and sed imentation kinet ics in normal and diabetic patients. Method: Clinical records of (40) normal vol unteers and diabetic patients from Educational Kadhimya Hospital were included in th is study. Results: In th is method, the resu lts of aggregation is presented in a time based graph. from which the slope (rate of aggregation can be calculated). Diabetic sample showed a shorter time of di ffe rent aggregation and sedime ntation stages. Samples from diabetic patients showed a lot of variabi lity in regard with different stages of aggregation. These changes were correlated well with the abnormal ity in their proteins. Conclusion: In diabetes mellitus a lot of rheological abnormalities could occur. like hyperglycemia. changes in lipid profiles and serum proteins and the ir sequel on the viscos ity of blood on one hand and the structural and fu nctional abnormalities of erythrocyte on the other hand. These modifications in the cellular properties and medium composition of blood in diabetic patients will affect the aggregation kinet ics of erythrocytes, which may play a role in the pathogenesis of diabet ic complication
