Author/Authors :
Safaralizadeh, R. tehran university of medical sciences tums - Immunology, Asthma and Allergy Research Institute, تهران, ايران , Siavoshi, F. university of tehran - Faculty of Sciences, تهران, ايران , Malekzadeh, R. tehran university of medical sciences tums - Digestive Disease Research Center, تهران, ايران , Akbari, M.R. tehran university of medical sciences tums - Digestive Disease Research Centre, تهران, ايران , Derakhshan, M.H. tehran university of medical sciences tums - Digestive Disease Research Centre, تهران, ايران , Sohrabi, M.R. tehran university of medical sciences tums - Digestive Disease Research Centre, تهران, ايران , Massarrat, S. tehran university of medical sciences tums - Digestive Disease Research Center, تهران, ايران
Abstract :
The occurrence of strains resistant to metronidazole is causing failure of the 4-drug regimen for eradication of Helicobacter pylori in the Islamic Republic of Iran. This study compared the in vitro efficacy of furazolidone with metronidazole, clarithromycin, amoxicillin and tetracycline in 70 H. pylori isolates from dyspeptic patients. Of the isolates, 33% were resistant to metronidazole but all were susceptible to furazolidone. Furazolidone could be considered as an appropriate substitute for metronidazole for H. pylori infections
