Author/Authors :
Hamkar, R. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Mahmoodi, M. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Nategh, R. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Jelyani, K.N. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Eslami, M.B. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Mohktari-Azad, T. tehran university of medical sciences tums - School of Public Health, تهران, ايران
Abstract :
In this study in the Islamic Republic of Iran 365 measles cases were evaluated to distin- guish between primary infection with measles and reinfection due to secondary vaccine failure. All cases previously confirmed by detection of specific IgM were tested for IgG avidity. A secondary immune response was seen in 18.4% of patients. All unvaccinated patients (16.7%) showed a primary immune response. Of 244 patients with documented vaccination, 75.8% showed a primary immune response and 24.2% showed a secondary immune response, thereby indicating a secondary vaccine failure. Almost all measles reinfections (99%) were seen in patients 10 years old, indicating that vaccination for 10-year-old children is recommended.
