Title of article
Primary and acquired drug resistance in childhood tuberculosis
Author/Authors
Khalilzadeh, S. shahid beheshti university of medical sciences - Massih Daneshvari Hospital - National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Boloorsaz, M.R. shahid beheshti university of medical sciences - Massih Daneshvari Hospital - National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Safavi, A. shahid beheshti university of medical sciences - Massih Daneshvari Hospital - National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Farnia, P. shahid beheshti university of medical sciences - Massih Daneshvari Hospital - National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Velayati, A.A. shahid beheshti university of medical sciences - Massih Daneshvari Hospital - National Research Institute of Tuberculosis and Lung Disease, تهران, ايران
From page
909
To page
914
Abstract
This study determined the resistance pattern of Mycobacterium tuberculosis to 4 first-line anti-tuberculosis drugs in children with pulmonary tuberculosis at the Iranian National Research Institute of Tuberculosis and Lung Diseases from 1999 to 2004. There were 350 children with positive cultures over the study period: 7 (2%) were resistant to at least one of the 4 anti-tuberculosis drugs. Primary resistance was detected in 4 cases and secondary resistance in 3 cases. Most cases (6) were among Afghan refugees. Resistance to rifampicin both in primary and secondary resistances was high, showing that children in the Islamic Republic of Iran face the threat of drug-resistant tuberculosis transmission.
Journal title
Eastern Mediterranean Health Journal
Journal title
Eastern Mediterranean Health Journal
Record number
2638423
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