Title of article
Platelet storage time and cytokine (IL-2R, IL-8, TNF-α) levels
Author/Authors
Bayraktarogğlu, Z. University of Gaziantep - Department of Paediatrics and Transfusion Medicine, Turkey , Yılmaz, N. University of Gaziantep - Department of Biochemistry, Turkey , Çicek, H.K. University of Gaziantep - Department of Biochemistry, Turkey , Karafak, A. University of Gaziantep - Department of Biochemistry, Turkey , Gül, E. State Hospital of Zekai Tahir Burak, Turkey
From page
79
To page
84
Abstract
This study investigated whether cytokine accumulation in plasma of platelet concentrates obtained from single apheresis donors was beyond the acceptable limits of white blood cell contaminattion at different storage time-points. Samples were obtained from 11 voluntary apheresis donors. All products were heavily contaminated with leukocytes. Sampling times from stored platelets were 0, 1, 3, 5 days respectively. Platelet, white blood cell counts and cytokines (IL-2R, IL-8 and TNF-α) were measured. The study found significant cytokine accumulation during 5 days of storage time in leukocyte contaminated platelet concentrates, suggesting that the platelet storage time has an effect on IL-2R levels.
Journal title
Eastern Mediterranean Health Journal
Journal title
Eastern Mediterranean Health Journal
Record number
2638655
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