Author/Authors :
Osman, A. King Faisal Specialist Hospital and Research Centre - Psychiatric Department, Saudi Arabia , Marghalani, M. Jeddah Psychiatric Hospital, Saudi Arabia , Turkistani, I.Y.A Al-Noor Hospital - Department of Psychiatry, Saudi Arabia , Al-Swaf, M. King Fahad General Hospital - Department of Psychiatry, Saudi Arabia , Bin Sadiq, B. King Faisal Specialist Hospital and Research Centre - Department of Family Medicine and Medical Statistics, Saudi Arabia
Abstract :
We carried out a retrospective descriptive study to determine prevalence and risk factors for tardive dyskinesia (TD) among psychotic patients treated with conventional neuroleptics in 4 centres in Saudi Arabia. Records of patients who had been taking 1 conventional neuroleptic for 6 months from January 1997 to December 2000 were examined; 151 patients were included in the final analysis. Only 51 had TD; another 59 (6.8%) patients had drug-induced Parkinson disease. Duration of treatment (P 0.001), higher doses of neuroleptics (P 0.01) and age over 40 years (P 0.01) were associated with TD. A statistically significant difference in prevalence was found between Arabs (23.5%) and Afro- Arabs (45.5%) (P 0.01). Overall prevalence of TD among psychotic patients was 5.9%.