Title of article
Study the Prophylactic Role of Anti-Type IV Pili (fimbriae) Antibody Against Pulmonary Infection Caused by P.aeruginosa in vivo (mice)
Author/Authors
abu resha, rasmia a. university of baghdad - college of science - department of biology, Iraq , al-zubaidy, basma b. university of baghdad - college of science for women - department of biology, Iraq
From page
998
To page
1008
Abstract
This study was aimed to investigate the effect of anti- type 4 pili antibody in prevention pulmonary infections caused by P. aeruginosa in vivo. This was achieved by Evaluation of biofilm formation by the microtiter plate method to select P.aeruginosa isolate with highest biofilm formation capacity, Extraction and the partial purification of type IV pili from the selected isolate, then Preparation of type IV pili antibodies by rabbit immunization. The lung histological sections of non immunized mice were severly damaged ,while the damage were markedly decrease in the lung of immunized mice with anti-type 4 pili antibody.
Keywords
Anti , type IV pili (fimbriae) antibody , P.aeruginosa , cystic fibrosis
Journal title
Iraqi Journal Of Science
Journal title
Iraqi Journal Of Science
Record number
2638948
Link To Document