Title of article
Use of the AMPLIFIEDTM Mycobacterium tuberculosis direct test for the diagnosis of tuberculosis
Author/Authors
Kalafati-Tzimaka, E. Pneumonological Clinic Laboratory - Department of Mycobacteria Tuberculosis of Northern Greece , Georgitzikis, I. Pneumonological Clinic Laboratory - Department of Mycobacteria Tuberculosis of Northern Greece , Delikatzi, D. Pneumonological Clinic Laboratory - Department of Mycobacteria Tuberculosis of Northern Greece , Chatzidimitriou, D. Pneumonological Clinic Laboratory - Department of Mycobacteria Tuberculosis of Northern Greece , Tzimaka, M. Aristotle University of Thessaloniki - Pneumonological Clinic - Department of Mass Media Communication, Greece , Patakas, D. Aristotle University of Thessaloniki - Pneumonological Clinic, Greece
From page
1119
To page
1119
Abstract
A comparative analysis was made of 3 conventional tests for tuberculosis (TB) versus a DNA probe technique among suspected TB patients at a reference centre in Greece. During 2004, we tested 2961 biological specimens from 2234 patients with the following methods: Ziehl–Neelsen staining, Löwenstein−Jensen culture, BACTEC mycobacteria growth indicator tubes (MGIT) and the Gen-Probe AMPLIFIEDTM Mycobacterium tuberculosis direct test (MTD). Of a total of 136 TB patients diagnosed and under anti-TB treatment, 133 of them (98%) were positive by amplified MTD. There were 112 TB (82%) detected by the MGIT method, 102 (75%) by Löwenstein–Jensen culture and 75 (55%) by Ziehl–Neelsen staining. Using MTD the positive result is ready within hours compared with days or weeks.
Journal title
Eastern Mediterranean Health Journal
Journal title
Eastern Mediterranean Health Journal
Record number
2640112
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