Author/Authors :
Ibrahim, N.K.R. King Abdul-Aziz University - Faculty of Medicine - Department of Family and Community Medicine, Saudi Arabia , Al Ashakar, M.S. Alexandria University - Faculty of Dentistry, Egypt , Gad, Z.M. Alexandria University - High Institute of Public Health - Department of Epidemiology, Egypt , Warda, M.H. Alexandria University - Faculty of Dentistry - Department of Maxillo-Facial and Plastic Surgery, Egypt , Ghanem, H. Alexandria University - Faculty of Medicine - Department of Clinical Oncology, Egypt
Abstract :
A retrospective cohort study was conducted to determine the 5-year survival and prognostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996–2000. Survival analysis was conducted using Kaplan–Meier curves, and multivariate Cox regression analysis. The overall 5-year survival rate was 30.8%. Multivariate analysis showed that significant prognostic factors for survival were tumour stage (hazard ratio = 2.39; 95% CI: 1.41–11.72), tumour site and patient’s age. Secondary prevention of oral cancers can be conducted through examination of the oral cavity to find precancerous and early cancerous lesions and hence improve survival.
