Effects of aqueous extract of Hibiscus sabdariffa L. on some biochemical indices of liver and kidney function in male albino rats

The present study aimed to investigate the effects of aqueous extract of flowersof Hibiscus sabdariffa onliver and kidneyfunction in male albino rats.Thirty male albino rats were randomly divided into five groups,six rats for each group.The extract was administered orally in doses of 0 ,25, 50,100 and 200mg/kg body weight for 28days.Blood samples were taken for biochemical assaysThe result showed There was no significant difference(P 0.05) in the liver and kidney to body weight ratio ,levels of ALP, AST, ALT, Directbilirubin, Total bilirubin,Sodium, Potassium,Calcium,Bicarbonate, Albumin, Chloride, Urea, Uric acid, creatinine and total protein of the treated rats when compared with the control.This study suggested that the aqueous extract of H. sabdariifawas nothepatoxicand nephrotoxic effects at the doses administered.