Author/Authors :
Tabarsi, P. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Baghaei, P. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Hemmati, N. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Mirsaeidi, M. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Kazempour, M. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Mansouri, D. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران , Masjedi, M.R. shahid beheshti university of medical sciences - Mycobacteriology Research Centre, National Research Institute of Tuberculosis and Lung Disease, تهران, ايران
Abstract :
We compared the effectiveness of 2 treatment regimens for isoniazid-resistant tuberculosisz(TB) in 42 patients attending a TB referral centre in the Islamic Republic of Iran. The patients were divided into 2 treatment groups: 26 received the 6-month standard HRZE treatment and 16 received a modified zreatment of RZE for 6 months. There were no significant differences in age or sex of the groups. With the standard method of treatment, 21 (80.8%) patients were cured, 4 (15.4%) resulted in treatment failure, and 1 (3.8%) died. In the modified treatment group, 16 (100%) patients were cured. These differences were not statistically significantly different (P = 0.194).