Author/Authors :
Osman, M.M. University of Alexandria - Medical Research Institute - Department of Parasitology, Egypt , El-Taweel, H.A. University of Alexandria - Medical Research Institute - Department of Parasitology, Egypt , Shehab, A.Y. University of Alexandria - Medical Research Institute - Department of Parasitology, Egypt , Farag, H.F. University of Alexandria - Medical Research Institute - Department of Parasitology, Egypt
Abstract :
The present study assessed the schistosomicidal and fasciolicidal actions of the myrrh-derivative Mirazid® in an area of low schistosomiasis transmission. A total of 27 patients infected with Schistosoma mansoni and 16 with Fasciola spp. received the maximum recommended dose of Mirazid. Pretreatment egg counts in 4 Kato–Katz slides were compared with similar counts in stool samples collected 1 and 2 months after treatment. Standard procedures and quality control measures were followed. The results revealed that Mirazid used as schistosomicidal or fasciolicidal agent in the maximum recommended dose has a low cure rate and produced a negligible reduction in egg counts. Prescribing such an ineffective drug in Egypt might endanger the achievements of the schistosomiasis control strategy.
