Author/Authors :
Samimi-Rad, K. tehran university of medical sciences tums - School of Public Health - Department of Virology, تهران, ايران , Hosseini, M. tehran university of medical sciences tums - School of Public Health - Department of Epidemiology and Biostatistics, تهران, ايران , Mobeini, G. tehran university of medical sciences tums - School of Public Health - Department of Virology, تهران, ايران , Asgari, F. tehran university of medical sciences tums - School of Public Health - Department of Virology, تهران, ايران , Alavian, S.M. baqiyatallah university of medical sciences - Research Centre for Gastroenterology and Liver Disease, ايران , Tahaei, M.E. tehran university of medical sciences tums - School of Public Health - Department of Virology, تهران, ايران , Salari, M.H. tehran university of medical sciences tums - School of Public Health - Department of Bacteriology, تهران, ايران
Abstract :
A cross-sectional study was made of the prevalence of HCV and associated risk factors in 382 multitransfused patients and haemodialysis staff in Yadz province in 2006. Of those tested for anti-HCV antibodies, 50.6% of patients with inherited bleeding disorders, 11.8% with thalassaemia and 5.0% undergoing haemodialysis were seropositive. First transfusion before 1996 (when blood donor screening started) was the common risk factor associated with HCV infection. Only 1/52 haemodialysis staff members was HCV infected (an intravenous drug user). Infection control measures were poor in all centres. In patients with inherited bleeding disorders genotype 1 (65.0%) was the predominant followed by genotype 3 (35.0%). The results provide evidence that blood donor screening and use of virus-inactivated factor concentrates have lowered the risk of HCV infection among multi-transfused patients.
