In vitro antifungal activity of Satureja Khuzestanica Jamzad against Cryptococcus neoformans

Objective: Finding the antifungal activity of Satureja Khuzestanica Jamzad extract against Cryptococcus neoformans isolates. Methodology: The dilution in agar method was used to test the plant extracts against C. neoformans. The minimum inhibitory concentration (MIC) was described as the lowest concentration capable to inhibit any visible fungal growth. All nine C. neoformans strains used in this study were environmental isolates. Results: The MIC value of Satureja Khuzestanica against C. neoformans isolates observed in this study demonstrated that the extract of this plant have antifungal activity. The MIC of extract of Satureja Khuzestanica ranged from 62.5-2000 μg/ml-1. The extract of this plant at concentration of 500 μg/ml-1 inhibited 78% of C. neoformans isolates. Conclusion: This study demonstrated that the extract of Satureja Khuzestanica has anticrptococcal activity. Our work open viewpoints of find more efficient medicines of herbal origin in the treatment of fungal mycoses