Title of article :
Prevalence of thalassaemia, iron-deficiency anaemia and glucose-6-phosphate dehydrogenase deficiency among Arab migrating nomad children, southern Islamic Republic of Iran
Author/Authors :
Pasalar, M. shiraz university of medical sciences - Haematology Research Centre, Nemazee Hospital, ايران , Mehrabani, D. shiraz university of medical sciences - Stem Cell and Transgenic Technology Research Centre - Department of Pathology, ايران , Afrasiabi, A. shiraz university of medical sciences - Haematology Research Centre, Nemazee Hospital, ايران , Mehravar, Z. shiraz university of medical sciences - Haematology Research Centre, Nemazee Hospital, ايران , Reyhani, I. shiraz university of medical sciences - Stem Cell and Transgenic Technology Research Centre - Department of Pathology, ايران , Hamidi, R. shiraz university of medical sciences - Haematology Research Centre, Nemazee Hospital, ايران , Karimi, M. shiraz university of medical sciences - Haematology Research Centre, Nemazee Hospital, ايران
Abstract :
This study investigated the prevalence of iron-deficiency anaemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency and β-thalassaemia trait among Arab migrating nomad children in southern Islamic Republic of Iran. Blood samples were analysed from 134 schoolchildren aged 18 years (51 males, 83 females). Low serum ferritin ( 12 ng/dL) was present in 17.9% of children (21.7% in females and 11.8% in males). Low haemoglobin (Hb) correlated significantly with a low serum ferritin. Only 1 child had G6PD deficiency. A total of 9.7% of children had HbA2 ≥ 3.5 g/ dL, indicating β-thalassaemia trait (10.8% in females and 7.8% in males). Mean serum iron, serum ferritin and total iron binding capacity were similar in males and females. Serum ferritin index was as accurate as Hb index in the diagnosis of iron-deficiency anaemia. A high prevalence of β-thalassaemia trait was the major potential risk factor in this population.
