Author/Authors :
Izadi, S. zahedan university of medical sciences - School of Public Health, Health Promotion Research Centre, ايران , Shahmahmoodi, S. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Zahraei, S.M. Ministry of Health and Medical Education - Centre for Communicable Disease Control, ايران , Dorostkar, F. tehran university of medical sciences tums - School of Public Health, تهران, ايران , Majdzadeh, S.-R. tehran university of medical sciences tums - School of Public Health, تهران, ايران
Abstract :
Despite high coverage rates of polio vaccine in the Islamic Republic of Iran, the seroconversion rates of infants may be inadequate. This study measured seroprevalence of antibodies against poliovirus serotypes 1 to 3 (PV1, PV2 and PV3) in 7-month-old infants who had received at least 4 doses of trivalent oral polio vaccine. A serosurvey was conducted in 2010 in rural areas of Chabahar, Sistan-va-Baluchestan province. Using cluster sampling, 72 eligible infants were tested for antibody against the 3 poliovirus serotypes according to WHO guidelines. Antibody titres ≥ 1:10 were considered positive. The seropositive rates for antibody against PV1, PV2 and PV3 were 84.7%, 95.8% and 70.8% respectively. Only 63.9% of participants were seropositive for antibodies against all 3 poliovirus serotypes. Except for PV2, the seroprevalence of antibody against the other 2 poliovirus serotypes, especially PV3, was unsatisfactory.
