Interpretation of Maturing Trilineage Hematopoiesis

Background: Normal adult bone marrow occupies the medullary spaces of large bones. The mainfunction of bone marrow is the production of blood cells (hematopoiesis). Bone marrow is composed ofa matrix requisite for hematopoiesis as well as erythriod precursors, myeloid precursors with monocytemacrophage system, megakaryocytes, lymphocytes, plasma cells, blood vessels and stroma.Interpretation of bone marrow maturing trilineage hematopoiesis includes the assessment of thematuration sequence and morphologic features for each lineage. Aim: This review presents detailed guidelines for interpretation of bone marrow maturing trilineagehematopoiesis according to the cell line and the pathologic condition. .