Title of article :
Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl2O4 as an effective catalyst
Author/Authors :
Safari, Javad university of kashan - Faculty of Chemistry - Department of Chemistry, Laboratory of Organic Chemistry Research, كاشان, ايران , Gandomi-Ravandi, Soheila university of kashan - Faculty of Chemistry - Department of Chemistry, Laboratory of Organic Chemistry Research, كاشان, ايران , Akbari, Zahra university of kashan - Faculty of Chemistry - Department of Chemistry, Laboratory of Organic Chemistry Research, كاشان, ايران
Abstract :
An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol.
Keywords :
Four , component reaction , One , pot synthesis , Ultrasonic irradiation , Imidazole
Journal title :
Journal of Advanced Research
Journal title :
Journal of Advanced Research
