Title of article :
DETERMINATION OF TOXIC METALS IN SOME HERBAL DRUGS THROUGH ATOMIC ABSORPTION SPECTROSCOPY
Author/Authors :
HINA, BUSHRA University of Karachi - Faculty of Pharmacy - Department of Pharmacognosy, Pakistan , RIZWANI, GHAZALA HAFEEZ University of Karachi - Faculty of Pharmacy - Department of Pharmacognosy, Pakistan , NASEEM, SHAHID University of Karachi - Department of Geology, Pakistan
From page :
353
To page :
358
Abstract :
This study presents a picture of occurrence of heavy metals (Pb, Cd, Cu, Cr, Co, Fe, Ni, Zn) in some selected valuable herbal drugs (G. glabra, O. bracteatum, V. odorata , F. vulgare, C. cyminum, C. sativum, and Z. officinalis) purchased from three different zones (southern, eastern, and western) of Karachi city using atomic absorption spectrophotometer. Heavy metal concentrations in these drugs were found in the range of: 3.26-30.46 for Pb, 1.6-4.91 for Cd, 0.65-120.21 for Cu, 83.74-433.76 for Zn, 1.61-186.75 for Cr, 0.48-76.97 for Ni, 5.54-77.97 for Co and 65.68-1652.89 μg/g for Fe. Percentage of heavy metals that were found beyond the permissible limits were: 71.4% for Pb, 28.51% for Cd, 14.2% for Cu, and 9.5 % for Cr. Significant difference was noticed for each heavy metal among herbal drugs as well as their zones of collection using two way ANOVA followed by least significant (LSD) test at p 0.05.Purpose of this research is to detect each type of heavy metal contaminant of herbal drugs by environmental pollution, as well as to highlight the health risks associated with the use of such herbal drugs that contain high levels of toxic heavy metals.
Keywords :
Atomic absorption spectrophotometer , environmental pollution , heavy metal toxicity , herbal drugs.
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
Record number :
2647437
Link To Document :
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