Author/Authors :
Abdullah Kohat University of Science and Technology - Department of Chemistry, Pakistan , Inayat, Humaira PCSIR labs Complex Peshawar - Medicinal Botanic Center, Pakistan , Khan, Haroon Gandhara University - Gandhara College of Pharmacy, Pakistan , Khan, Lajber PCSIR labs Complex Peshawar - Medicinal Botanical Centre, Pakistan , Khan, Mohammad Iqbal Kohat University of Science and Technology - Department of Chemistry, Pakistan , Hassan, Sohail University of Karachi - Faculty of Pharmacy - Department of Pharmaceutical Chemistry, Pakistan , Khan, Murad Ali Kohat University of Science and Technology - Department of Chemistry, Pakistan
Abstract :
Joshanda is a polyherbal product, commonly practicing in inflammation of upper respiratory tract as tea. The present study was conducted to find out its antimicrobial, phytotoxic, leishmanicidal and cytotoxic activities. The decoction of the product showed profound activity against Gram positive tested pathogens especially S. aureus 36.5 mm zone of inhibition at 8.0μg/ml. However, it was inactive against C. albicans. Closed correlation was observed between two methods in terms of results. It had potent phytotoxic activity (75%). However, it was devoid of any activity leishmanicidal and cytotoxic activity. Phytochemical studies of Joshanda showed the presence of various pharmacologically active groups.
Keywords :
Joshanda , decoction , antibacterial , antifungal , phytotoxic , phytochemicals
