Author/Authors :
ziapour, p. cell and molecular research lab, amol research center, pasteur institute of iran, amol, iran, parasitiology department, amol research center, pasteur institute of iran, ايران , ataee, r. cell and molecular research lab, amol research center, pasteur institute of iran, ايران , shadifar, m. parasitiology department, amol research center, pasteur institute of iran, ايران , vaillancourt, c. biochemistry department, armand frappier institute, Canada , ahmadi, a. biochemistry lab, amol research center, pasteur instute of iran, ايران , jafari-sabet, m. aja university of medical sciences, ايران , ataee, a. babol university of medical sciences, ايران
Abstract :
Colorectal cancer is one of the most common malignancy in the world and the second cancer-related death, many molecular and genetic aspects of this disease have been cleared as chromosomal instability and the role of some key proteins as WNT/β catenin, trypsin and others. Also recently the role of folate turnover and some neurotransmitters as serotonin were also considered. The scope of this review is to describe some details about new molecular pathways suggested for occurrence or progress of this disease. © 2011 RIGLD, Research Institute for Gastroenterology and Liver Diseases.
Keywords :
Colorectal cancer , Molecular pathology , Serotonin , Trypsin , WNT protein
