Title of article :
SALIVARY VITAMIN E AND C IN LICHEN PLANUS
Author/Authors :
Rai, Balwant Post Graduate Institute of Medical Science - Government Dental College, India , Kharb, Simmi Post Graduate Institute of Medical Science - Pt Bhagwat Dayal Sharma, India , Jain, Rajnish Post Graduate Institute of Medical Science - Government Dental College, India , Anand, S. C. Post Graduate Institute of Medical Science - Government Dental College, India
Abstract :
Background: Lipid peroxidation may be involved in the pre-cancer process and essential nutrients that can scavenge free radicals, such as vitamin E and C constitute a strong line of defense in retarding free radical induced cellular damage. The present study was planned to investigate the salivary levels of vitamin C and E in patients with oral Lichen planus. Material Methods: It was a comparative cross-sectional study, conducted at Jain diagnostic Centre, New Delhi, India. Antioxidant vitamin E and C levels were estimated in 10 patients of oral Lichen planus and 7 healthy persons served as controls. Results: The salivary levels of vitamin C were significantly decreased in patients with oral Lichen planus as compared to controls (p 0.05). Also, vitamin E levels were low in oral Lichen planus as compared to controls (p 0.05). There was a significant positive correlation between fall in vitamin C and vitamin E (r=0.65, p 0.05). Conclusion: Antioxidant defenses (vitamin E and C) are compromised and oxidative stress increased in patients with oral Lichen planus
Keywords :
Oral Lichen planus , Antioxidant , Vitamin E , Vitamin C , Saliva
Journal title :
GOMAL JOURNAL OF MEDICAL SCIENCES
Journal title :
GOMAL JOURNAL OF MEDICAL SCIENCES
