Title of article :
Dose Optimisation of 18F-Flurodeoxyglucose for Whole Body PET Oncology Examination in CDNI of UPM
Author/Authors :
Hishar, H. Universiti Putra Malaysia - Centre for Diagnostic Nuclear Imaging, Malaysia , Salasiah, M. Universiti Putra Malaysia - Centre for Diagnostic Nuclear Imaging, Malaysia , Fathinul Fikri, A. S. Universiti Putra Malaysia - Centre for Diagnostic Nuclear Imaging, Malaysia , Nordin, A. J. Universiti Putra Malaysia - Centre for Diagnostic Nuclear Imaging, Malaysia
Abstract :
A shift to administration of optimal dose of 18F-FDG between 4 and 5 MBq/kg from the current practice of higher doses potentially yields a reasonable-to-excellent PET image. For this purpose, whole-body MIP images of 32 patients (23 men, 9 women, age 51.9 ± 13.7 years), administered with 18F-FDG (activity 5.3 ± 0.5 MBq/kg, 45 minutes uptake time) for whole-body PET/CT examinations, were evaluated. Image quality was assessed visually by two radiologists using a three-point scoring scale: poor, reasonable and excellent. The interobserver agreement revealed a kappa value higher than 0.7. Therefore, the utilisation of 18F-FDG dose between 4 and 5MBq/kg is considered an optimum dose for whole-body PET/CT examination.
Keywords :
18F , FDG , PET , CT , PET image quality , optimum dose , administered dose , body weight (kg) , MIP
Journal title :
Pertanika Journal of Science and Technology ( JST)
Journal title :
Pertanika Journal of Science and Technology ( JST)
