First Reported Case of Hereditary Bisalbuminaemia in Pakistan

A 50 year old female patient demonstrated double peaks of albumin on serum protein electrophoresis (SPE).Patient s detailed medical history was taken and investigations were carried out to rule out systemic causes.Serum electrophoresis was also done on 5 of patient s children. Mixing studies were performed in gradually decreasing concentration of bisalbuminemic serum.Hereditary Bisalbuminaemia with the variant albumin showing slower mobility, was observed.