Study of theImmunopathological Changes Induced by Pseudomonas aerugenosa in Mice Treated with Alcoholic Apium greveolense extract and Immunized with Whole Sonicated Salmonella typhimurium Antigens

In order to know the efficacy of whole sonicated antigen with or without celery extract on the challenge with viable virulent Pseudomonas aeruginosa , thirty-five healthy white mice, both sex, aged between 6-8 weeks were randomly divided into five groups and treated as following: The 1st group (n= 10) immunized with WSSAgs (0.5ml/lmg protein) S/C as primary dose followed by second dose after two weeks. 2-The 2nd group(n=10) administrated daily dose of 0.5ml of alcoholic celery extract (Concentration of protein 600 mg/kg BW) orally for 30 days and at the same time treated as 1st group. 3- The 3rd group (n=5) administrated orally with alcoholic celery extract only with same dose and time of the2nd group. The 4th and 5th group (5 animals each) treated as control positive and negative respectively.