Effect of coffee on some physiological parameters

This present study was undertaken to search out the effect of coffee containing caffeine on some physiological parameters in adult male rabbits. Ten adult male rabbits were randomly divided into two equale groups, control group (C): rabbits of this group were allowed to ad libitum supply of drinking water, treated group (T): rabbits of this group were allowed to ad libitum supply of drinking water containing 100 mg/kg b.w of coffee, blood samples were collected at 15 and 30 days of the experiment, Blood was drawn by cardiac puncture technique for measuring the following parameters: blood glucose concentration, total cholesterol (TC), blood urea concentration and haemoglobin concentration, section from kidney and liver were taken at the end of the experiment for histological study. The results revealed that coffee consumption at dose 100 mg/kg b.w in drinking water for 30 days cause a significant decrees (p 0.05) in blood glucose concentration and a significant increase (p 0.05) in total cholesterol and blood urea concentration in addition to non significant reduction (p 0.05) in haemoglobin concentration. No histological changes in kidney and liver tissue in the treated group as compared to control group .Results of this study showed that the coffee consumption negatively effected the total cholesterol ,blood urea, and haemoglobin concentration in conclusion the regular consumption of coffee negatively effect on health of both human and animals.