Title of article :
Scleroderma renal crises: case report and review of literature
Author/Authors :
Sabir, Omer Fatima Memorial Hospital - Department of Medicine, Division of Nephrology, Pakistan , Younas, Haroon Fatima Memorial Hospital - Department of Medicine, Division of Nephrology, Pakistan , Tanvir, Imrana Fatima Memorial Hospital - Department of Medicine, Division of Nephrology, Pakistan , Tarif, Nauman Fatima Memorial Hospital - Department of Pathology, Division of Histopathology, Pakistan
Abstract :
Scleroderma (systemic sclerosis) is a connective tissue disorder which involves skin, gastrointestinal tract, kidneys and lungs with considerable morbidity. Scleroderma renal crisis is a well-known severe form of renal involvement, characterised by the presence of high blood pressure with variable degrees of renal insufficiency. We report a case of scleroderma renal crisis diagnosed on the basis of history of scleroderma, high blood pressure and renal dysfunction. The biopsy confirmed the typical histopathological findings. We discuss herein the management of the case and reviewthe literature.
Keywords :
Systemic scleroderma , Scleroderma renal crisis , Angiotensin , converting enzyme inhibitors.
Journal title :
Journal of the Pakistan Medical Association (Centre) JPMA
Journal title :
Journal of the Pakistan Medical Association (Centre) JPMA