Author/Authors :
Bawany, Faizan Imran Dow University of Health Sciences (DUHS), Pakistan , Khan, Muhammad Shahzeb Dow University of Health Sciences (DUHS), Pakistan , Naeem, Mohammad Rhode Island Hospital, USA , Shoaib, Atif Bilal Dow University of Health Sciences (DUHS), Pakistan
Abstract :
Madam, cetirizine hydrochloride, an antihistamine, is the active constituent of Zyrtec® that functions as competitive peripheral H1 receptor inhibitor.Cetirizine is known to have reduced blood-brain barrier penetration due to its larger mass, lipophobic properties and increased attraction for peripheral H1 receptors.