Author/Authors :
Attarzadeh, Abbas shiraz university of medical sciences - Poostchi Eye Research Center, شيراز, ايران , Hoseinirad, Abbas shiraz university of medical sciences - Poostchi Eye Research Center, شيراز, ايران , Farvardin, Majid shiraz university of medical sciences - Poostchi Eye Research Center, شيراز, ايران , Talebnejad, Mohammad-Reza shiraz university of medical sciences - Poostchi Eye Research Center, شيراز, ايران , Alipour, Abbas shiraz university of medical sciences - Poostchi Eye Research Center, شيراز, ايران
Abstract :
Purpose: To evaluate the association between fixation preference (FP) and amblyopia instrabismic patients.Methods: This study includes 50 patients with horizontal, vertical or mixed strabismusof at least 10 prism diopters. Best-corrected monocular visual acuity (VA) was measured using Snellen E-chart and the presence of amblyopia was determined accordingly; FP was evaluated and graded from 0 to 3.Results: Of 50 patients, including 27 female and 23 male subjects, 29 (58%) patients hadFP but 18 (36%) subjects were truly amblyopic. Overall, the sensitivity and specificity ofFP for detection of amblyopia was 88.9% and 59.4% respectively. The positive predictivevalue (PPV) and negative predictive value (NPV) were 55.2% and 90.5% respectively.Sensitivity, PPV and NPV were significantly higher in esotropic as compared toexotropic patients. Strong monocular FP was correlated with more than 3 lines ofinterocular difference (IOD) in visual acuity (P=0.001).Conclusion: Although FP is not an ideal method for diagnosis of strabismic amblyopia,it has high sensitivity, PPV and NPV in esotropic patients and in subjects with morethan 3 lines of IOD in VA.
