Author/Authors :
PRABHA, D.S. Bharathidasan University - National Facility for Marine Cyanobacteria - Department of Marine Biotechnology, India , KARTHIKEYAN, K. Bharathidasan University - Department of Animal Sciences, India , NAVANIETHA KRISHNARAJ, R. Kalasalingam University - Department of Biotechnology, India , AKILA, B.M. SRM University - Department of Biotechnology, India , HEMANTH, S. SRM University - Department of Biotechnology, India , HARIKRISHNAN, R. SRM University - Department of Biotechnology, India , ARCHUNAN, G. Bharathidasan University - Department of Animal Sciences, India , MALLIGA, P. Bharathidasan University - National Facility for Marine Cyanobacteria - Department of Marine Biotechnology, India
Abstract :
This study was carried out to investigate the effect of degraded coir pith based cyanobacterial culture filtrate on Rattus norvegicus. The culture filtrate containing phenolic compound was administered at a rate of 42 mg/Kg for 15 days and its effect on serum glucose, protein, creatinine, urea, uric acid, alkaline phosphate (ALP), serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT) and sperm analysis was studied. The results showed a significant reduction in the levels of serum glucose and liver marker enzymes while serum protein and renal function test showed normal level in both experimental and control rats. Also, a significant reduction in semen count was reported. The results suggested that the phenolic compound of the culture filtrate appears to be non toxic in the tested animals
Keywords :
phenolic compounds , released during degradation , Coir pith , Oscillatoria annae
