Oral intravascular papillary endothelial hyperplasia: a case report

Intravascular papillary endothelial hyperplasia (IPEH) is an unusual vascular lesion of proliferating endothelial cells. It is more frequently observed in extremities, particularly fingers. Oral IPEH is rare; it has been reported in lip, tongue, buccal mucosa and in one case only, at the angle of mouth. A misdiagnosis of angiosarcoma can be made in a case of IPEH due to similar histopathologic features. In this clinical report, we address a case of a 61-year-old male with an oral IPEH at the angle of the mouth, facing an edentulous site of maxillary right first premolar (extracted 10 years earlier). The patient mentioned a biting and suction habit of this lesion. Surgical removal was performed and histopathologic examination identified IPEH. Patient’s follow-up revealed an ischemic heart stroke 5 years after and no recurrence six years after surgery.