SYNTHESIS A NUMBER OF AZO COMPOUNDS DERIVED FROM GUANINE AND STUDYING THEIR BIOLOGICAL ACTIVITY ON PATHOGENIC BACTERIA

A series of compounds were prepared by coupling dizonium salts with guanine. The structures of the prepared compounds were identified by ultra violet ,infra red spectra and Elemental (C.H.N) analysis .The biological activity of these compounds was investigated on five genera of pathogenic bacteria: S. aureus , Str. viridans , Ps. aeruginosa , E. coli and Sh. dysenteriae using Disc diffusion method. Also the minimum inhibitory concentration (MIC) was calculated .It was found that these compounds have medium biological effect against these genera of bacteri