Association of Dugs with Psoriasis: A Review of Literature

Psoriasis is a common disorder in dermatologic practice. Though its exact etiology is still unknown but there are many internal and external factors contributing to the clinical course of the disease. There are several drugs described in the literature that have been associated with the initiation, exacerbation and aggravation of psoriasis. Depending on the relation to induction or exacerbation of psoriasis the drugs may be classified as drugs with strong casual relation with psoriasis, drugs with considerable but insufficient evidence of association and drugs with occasional association with aggravation or induction of the disease. Understanding of underlying pathogenesis is very important in the management of drug related psoriasis. This review included the most common causative agents in relation to psoriasis, their underlying pathogenesis, clinical manifestations and management of such cases.