Title of article
Double Aneuploidy - A Rare Condition : Report of Two Cases
Author/Authors
Habib, Saequa Department of Pathology - Bangabandhu Sheikh Mujib Medical University , Gulshana Banu, Sultana Department of Pathology - Bangabandhu Sheikh Mujib Medical University , Islam, Shahedul Department of Pathology - Bangabandhu Sheikh Mujib Medical University , Kawser, Ali Department of Paediatrics - Bangabandhu Sheikh Mujib Medical University
Pages
3
From page
171
To page
173
Abstract
The chance of two chromosome abnormalities occurring in one conceptus is rare. Here we report two cases of double aneuploidy with karyotype 48,XYY,+21 and 48,XXY,+21.The diagnosis was confirmed by cytogenetic analysis using peripheral blood followed by Giemsa banding technique. Clinically both the children had most of the phenotypic features of Trisomy 21. However phenotypic features of XYY were not present but the child with XXY had undescended right testis .The purpose of this communication is to report such rare disorders discovered as the result of the evaluation for Trisomy 21.
Keywords
Cytogenetics , double aneuploidy , Trisomy 21 , sex chromosomes
Journal title
Journal of Bangladesh College of Physicians and Surgeons
Serial Year
2014
Journal title
Journal of Bangladesh College of Physicians and Surgeons
Record number
2668311
Link To Document