Author/Authors :
Bhansali, Anil Postgraduate Institute of Medical Education and Research - Department of Endocrinology and Metabolism, INDIA , Dutta, Pinaki Postgraduate Institute of Medical Education and Research - Department of Endocrinology, INDIA , Reddy, K.S.S. Postgraduate Institute of Medical Education and Research - Department of Endocrinology, INDIA , Masoodi, Shariq R. Postgraduate Institute of Medical Education and Research - Department of Endocrinology, INDIA , Radotra, B.D. Postgraduate Institute of Medical Education and Research - Department of Pathology, INDIA , Kumar, Vijay Postgraduate Institute of Medical Education and Research - Department of Pathology, INDIA , Mittal, B.R. Postgraduate Institute of Medical Education and Research - Department of Nuclear Medicine, INDIA
Abstract :
Cancer of the thyroid is the most common endocrine malignancy. Most patients with well-differentiated thyroid carcinoma present with an asymptomatic thyroid nodule with or without regional lymphadenopathy or rarely with distant metastasis at diagnosis.Western series report a prevalence rate of 4% for metastasis outside the neck, but in an endemic iodine deficiency area like ours the overall prevalence of distant metastasis was 20%. In 17% of cases, metastases were detected synchronously and at multiple sites. Metastatic disease as the presenting manifestation is exceedingly rare. Patients with metastaticdisease are usually asymptomatic and rarely present with organ-specific symptoms. We describe patients with peculiar presentations. In patients the metastatic disease presented with unusual manifestationsfor the first time and one had a follicular thyroid carcinoma in a struma ovarii after total thyroidectomy.
