Title of article
Re: Lovastatin for Reduction of Leptin in Nondialysis Patients With Type 2 Diabetic Nephropathy
Author/Authors
Ahmadi, Farrokhlagha tehran university of medical sciences tums - Nephrology Research Center - Division of Nephrology, تهران, ايران , Mohebi-Nejad, Azin tehran university of medical sciences tums - Nephrology Research Center, تهران, ايران
From page
344
To page
349
Abstract
Dear Editor, We read with interest the article in the Iranian Journal of Kidney Diseases, by Gholamin and colleagues, “Lovastatin for Reduction of Leptin in Nondialysis Patients With Type 2 Diabetic Nephropathy.” There is controversy regarding leptin and vascular endothelial function. Leptin induces endothelium-dependent vascular relaxation by stimulating nitric oxide (NO). However, some believe that the leptin-induced vasodilatation is independent on NO and other vasoactive agents such as endothelium-derived hyperpolarizing factor (EDHF) or prostacyclins are possibly involved.
Journal title
Iranian Journal of Kidney Diseases (IJKD)
Journal title
Iranian Journal of Kidney Diseases (IJKD)
Record number
2670110
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