Author/Authors :
Kammoun, Khawla Hedi Chaker Hospital - Department of Nephrology, Tunisia , Kammoun, Khawla Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia , Jarraya, Faiçal Hedi Chaker Hospital - Department of Nephrology, Tunisia , Jarraya, Faiçal Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia , Makni, Saloua Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia , Makni, Saloua Habib Bourguiba Hospital - Department of Histopathology, Tunisia , Ben Mahmoud, Lobna Faculty of Medicine - Regional Center of Pharmacovigilance, Tunisia , Kharrat, Mahmoud Hedi Chaker Hospital - Department of Nephrology, Tunisia , Kharrat, Mahmoud Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia , Ben Hmida, Mohamed Hedi Chaker Hospital - Department of Nephrology, Tunisia , Ben Hmida, Mohamed Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia , Zeghal, Khaled Faculty of Medicine - Regional Center of Pharmacovigilance, Tunisia , Boudawara, Tahia Habib Bourguiba Hospital - Department of Histopathology, Tunisia , Hachicha, Jamil Hedi Chaker Hospital - Department of Nephrology, Tunisia , Hachicha, Jamil Faculty of Medicine - Renal Pathology Unit UR 12 ES 14, Tunisia
Abstract :
Ciprofloxacin is a commonly used antibiotic. Renal side effects are rare and are usually immune mediated. Clinical and experimental studies have suggested that crystalluria and crystal nephropathy occur in alkaline urine. Preexisting kidney function impairment, high dose of the medication, and advanced age predispose to this complication. We report a case of crystal nephropathy in a young woman treated with ciprofloxacin and a nonsteroidal anti-inflammatory drug.