Title of article
Antitussive Effect of Plantago lanceolata in Guinea Pigs
Author/Authors
BOSKABADY, M. H. mashhad university of medical sciences - Pharmacological Research Center of Medicinal Plants - Department of Physiology, مشهد, ايران , RAKHSHANDEH, H. mashhad university of medical sciences - Pharmacological Research Center of Medicinal Plants - Department of Physiology, مشهد, ايران , AFIAT, M. mashhad university of medical sciences - Pharmacological Research Center of Medicinal Plants - Department of Physiology, مشهد, ايران , AELAMI, Z. mashhad university of medical sciences - Pharmacological Research Center of Medicinal Plants - Department of Physiology, مشهد, ايران , AMIRI, S. mashhad university of medical sciences - Pharmacological Research Center of Medicinal Plants - Department of Physiology, مشهد, ايران
From page
143
To page
146
Abstract
Background: Several therapeutic effects including antiasthma and dyspnea have been described for Plantago lanceolata. In the present study the antitussive effect of this plant was evaluated. Methods: The antitussive effects of aerosols of two different concentrations of Soxhlet and macerated ethanolic extracts, codeine and saline were tested by counting the number of coughs produced due to aerosol of citric acid 10 min after exposing the animal to aerosols of different solutions (n=8 for each solution). Results: The results showed significant reductions of cough number observed in the presence of both concentrations of Soxhlet and macerated extracts of Plantago lanceolata as compared to saline treated group (p(LESS THAN)O.OOl). The reduced cough number observed in the presence of higher concentrations of extracts was not significantly different from that of lower concentrations ofLP. Furthermore, there was no significant difference between the cough numbers observed in the presence of both concentrations of the extracts with that of codeine. Conclusion: The ethanolic extracts of Plantago lanceolata have antitussive effects comparable with that of codeine
Keywords
Plantago lanceolata • antitussive effect. guinea pig • citric acid. codeine
Journal title
Iranian Journal of Medical Sciences (IJMS)
Journal title
Iranian Journal of Medical Sciences (IJMS)
Record number
2671161
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