Author/Authors :
Kara, Hasan Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey , Ak, Ahmet Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey , Bayır, Ayşegül Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey , Acar, Demet Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey , İstanbulluoğlu, Rabia Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey , Değirmenci, Selim Selçuk University - Selçuklu Faculty of Medicine - Department of Emergency Medicine, Turkey
Abstract :
Background: Bupropion is a new-generation monocyclic antidepressant that has been accidentally found to have potential effects on reducing nicotine addiction. It is structurally similar to stimulants such as amphetamine and inhibits dopamine and noradrenalin reuptake selectively. Case Reports: We report two cases with no history of epilepsy who took oral bupropion for depression and had generalised tonic-clonic type of seizures in their follow-ups. Conclusion: After an overdose of bupropion, clinical effects are seen primarily on the neurological, cardiovascular, and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucinations, coma, and seizures.
