Title of article
Balanced Chromosomal Translocation of Chromosomes 6 and 7: A Rare Male Factor of Spontaneous Abortions
Author/Authors
Resim, Sefa Kahramanmaraş Sütçü İmam University - Faculty of Medicine - Department of Urology, Turkey , Kadıoğlu, Ateş Istanbul University - Faculty of Medicine - Department of Urology, Turkey , Akman, Tolga Istanbul University - Faculty of Medicine - Department of Internal Diseases, Turkey , Bayrak, Ayşe Gül Istanbul University - Faculty of Medicine - Department of Internal Diseases, Turkey , Efe, Erkan Kahramanmaraş Sütçü İmam University - Faculty of Medicine - Department of Urology, Turkey
From page
250
To page
252
Abstract
Background: Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. Case Report: We report a man with balanced chromosomal translocations located at 6p22, and 7q22. His wife has a history of four spontaneous abortions. Conclusion: Couples with a history of abortions should be investigated cytogenetically, after other causes of miscarriages are excluded. The possibility of spontaneous abortions can be reduced with preimplantation genetic diagnosis (PGD) before embryo transfer.
Keywords
Balanced chromosomal translocation , spontaneous abortions , preimplantation genetic diagnosis
Journal title
Balkan Medical Journal
Journal title
Balkan Medical Journal
Record number
2671425
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