Author/Authors :
Açıkalın, Arbil Çukurova University - Faculty of Medicine - Department of Pathology, Turkey , Paydaş, Semra Çukurova University - Faculty of Medicine - Department of Medical Oncology, Turkey , Güleç, Ümran Küçükgöz Çukurova University - Faculty of Medicine - Department of Gynecology and Obstetrics, Turkey , Uğuz, Aysun Çukurova University - Faculty of Medicine - Department of Pathology, Turkey , Gümürdülü, Derya Çukurova University - Faculty of Medicine - Department of Pathology, Turkey
Abstract :
Background: Merkel cell carcinoma (MCC) is a rare cutaneous/mucosal malignancy with very aggressive biology and increasing incidence. Ovarian metastasis is an exceptionally rare site for MCC, and only two cases have been reported in the literature. Case Report: We report MCC with ovarian metastasis. A 34 year-old female with previously excised MCC from preauricular skin presented with a pelvic mass 15 months after first diagnosis. Anti-cytokeratin (CK) 20 positivity, LCA (leucocyte common antigen), and TTF-1 (Thyroid transcription factor-1) negativity confirmed metastatic ovarian MCC. There was no evidence of recurrence or metastasis at 12 months after salpingooopherectomy. Conclusion: MCC should be considered in the differential diagnosis of primary and metastatic undifferentiated small round cell tumors of the ovary.
Keywords :
Carcinoma , Merkel cell , metastasis ovarian , neoplasms
