Author/Authors :
Hossain, MM Jahangirnagar University - Department of Chemistry, Bangladesh , Muhib, MH Jahangirnagar University - Department of Chemistry, Bangladesh , Mia, MR Jahangirnagar University - Department of Chemistry, Bangladesh , Kumar, S Jahangirnagar University - Department of Pharmacy, Bangladesh , Wadud, SA Bangabhandhu Sheikh Mujib Medical University - Department of Ophthalmology, Bangladesh
Abstract :
In continuation of our study the in vitro antioxidant activity of some novel quinoxaline derivatives was investigated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method with respect to ascorbic acid. To determine the antioxidant activity, a number of substituted indoxyls (3A-G), cyclic ketones (2A-G), and quinoxalines (1A-G) were synthesized by both microwave and conventional heating methods. The present findings revealed that some quinoxalines and their precursors (1D, 1F, 1G and 2E) exhibited a marked scavenging effect on DPPH radical.
