The effect of sodium and ultra filtration profile combination and cold dialysate on hypotension during hemodialysis and its symptoms

BACKGROUND: One of the most prevalent side effects of hemodialysis is intradialytic hypotension and its symptoms. Using sodium profiles 3 and ultra filtration profile 3 and cold dialysate are the ways to overcome this problem. Since none of these methods can control this complication lonely, this study was to investigate the effect of combination of both methods on intradialytic hypotension. METHODS: This study was a crossover clinical trial in which 24 patients experiencing frequent intradialytic hypotension, underwent three different methods of treatments during 9 successive hemodialysis sessions. Group 1 used sodium profile 3 and ultra filtration profile 3, group 2 underwent hemodialysis with cold dialysate, and group 3 received combination of both methods. Blood pressure was controlled before, during (3 times) and after hemodialysis. Data were analyzed via SPSS15, by χ2 and ANOVA tests. RESULTS: Findings showed that although there was no significant difference concerning intradialytic hypotension and its symptoms in two groups of sodium profile 3 and ultra filtration profile 3 and cold dialysate and the combination group (p 0.05), there was a significant difference concerning the mean blood pressure in three groups (p 0.05). In combination group, drop of systolic and diastolic blood pressures were less than groups with each of the methods. CONCLUSIONS: Concerning the decreased rate of hypotension with combination method, nurses can use this method to decrease intradialytic hypotension and help the patients undergo hemodialysis for enough time and improve their quality of life.