Title of article :
Serological and Molecular Survey of Toxoplasma gondii Infection in Hemodialysis Patients with Chronic Renal Disease in Zahedan, Iran
Author/Authors :
Mirahmadi ، Hadi Department of Parasitology and Mycology - Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute, Faculty of Medicine - Zahedan University of Medical Sciences , Mehravaran ، Ahmad Department of Parasitology and Mycology - Faculty of Medicine, Infectious Diseases and Tropical Medicine Research Center, Resistant Tuberculosis Institute - Zahedan University of Medical Sciences , Sani Haidari ، Masoumeh Department of Parasitology and Mycology - Faculty of Medicine - Zahedan University of Medical Sciences , Rahmati-Balaghaleh ، Mansour Department of Parasitology and Mycology - Faculty of Medicine - Zahedan University of Medical Sciences , Raissi ، Vahid Department of Medical Parasitology and Mycology - Faculty of public health - Tehran University of Medical Sciences , Shafiei ، Reza Vector-borne Diseases Research Center - North Khorasan University of Medical Sciences
Abstract :
Background: Toxoplasma gondii is one of the most prevalent zoonotic opportunistic parasitic infections in the world. The aim of this study was to examine chronic and acute toxoplasmosis molecularly and serologically in Hemodialysis patients. Methods: A total of 238 serum samples of hemodialysis patients with chronic renal disease (119 samples) as case group and healthy individuals (119 samples) as control group were enrolled in Zahedan City, southeastern Iran. The molecular and serological detection of toxoplasmosis were conducted on all samples using nested-PCR and ELISA. Results: The prevalence rates of anti-T. gondii IgM and IgG and T. gondii DNA in the case group were respectively 0%, 44.5% and 29.4% and the corresponding values in the control group were 0.8%,23.5% and 2.52 % respectively (p≥0.05). Conclusion: In conclusion, preliminary Toxoplasma gondii infection screening is required using serological techniques, particularly in hemodialysis patients who are frequently exposed to hemodialysis so as to stop infection dissemination
Keywords :
Toxoplasma , Hemodialysis patients , Nested , PCR , Zahedan
Journal title :
Journal of Kerman University of Medical Sciences (JKMU)
Journal title :
Journal of Kerman University of Medical Sciences (JKMU)
