Study the Inhibitory Effect of Garlic Extract on S. aureus and E. coli of Multi-Resistance to Antibiotics

This Study aimed to investigate the effect of garlic extract against multidrug resistance of Staphylococcus aureus and E. coli isolated from urine. Isolates were identified by using biochemical tests. The susceptibility of these microorganisms towards the most effective antibiotics were studied by using disc diffusion method. The multidrug resistance microorganisms were challenged with garlic extract using serial dilutions and the technology of ELISA spectrophotometer. The results of this study showed that ten isolates of E. coli and eight isolates of Staphylococcus aureus out of sixty isolates were resistant to all antibiotics. Garlic extract significantly inhibits the growth of these bacteria in a concentration independent manner. This study showed that garlic extract exerts a promising antibacterial effect against multidrug resistance of Staphylococcus aureus and E. coli.