Author/Authors :
Destan Rudhani, Ibrahim University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Hemodialysis, Kosovo , Bajraktari, Gani University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Cardiology, Kosovo , Kryziu, Emrush University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Hemodialysis, Kosovo , Zylfiu, Bejtush University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Sadiku, Shemsedin University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Elezi, Ymer University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Rexhepaj, Nehat University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Cardiology, Kosovo , Vitia, Arber University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Emini, Merita University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Abazi, Murat University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Berbatovci-Ukimeraj, M. University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Kryeziu, Kaltrina University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Hsanagjekaj, Venera University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Korca, Hajrije University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Nephrology and Haemodialysis, Kosovo , Ukimeri, Aferdita University Clinical Center of Kosovo - Internal Medicine Clinic - Department of Cardiology, Kosovo
Abstract :
The aim of this prospective study was the assessment of left ventricular and right ventricular diastolic function in patients on hemodialysis (HD) and the correlation of this function with the duration of HD. The study included 42 patients (22 females and 20 males) with chronic renal failure (CRF), treated with HD, and 40 healthy subjects (24 females and 16 males) with no history of cardiovascular disease and with normal renal function, who constituted the control group. The groups were matched for age and sex. All study patients and control subjects underwent detailed history taking and physical examination. They also underwent electrocardiogram, echocardiography and biochemical and hematological blood analyses. Significant differences were noted between the two groups in the two-dimensional and M-mode echocardiography findings concerning aortic root dimension, transverse diameter of the left atrium, thickness of the inter-ventricular septum, thickness of the left ventricular posterior wall, left ventricular diastolic diameter, left ventricular systolic diameter, shortening fraction, ejection fraction as well as findings from the pulse Doppler study, including E wave, A wave, E/A ratio, deceleration time of E wave (DT-E), acceleration time of E wave (AT-E), tricuspid E and A waves (Etr and Atr) and Etr/Atr ratio. There were significant changes in HD patients without arterial hypertension as well in the control group subjects. Our study suggests that the left ventricular and left atrial dimensions as well as the left ventricular wall thickness are augmented in patients with CRF treated with HD compared with the control group. Additionally, the left and right ventricular diastolic function is also reduced in these patients. These differences were also noted in patients with CRF without arterial hypertension. Left ventricular diastolic dysfunction had no correlation with the duration of HD.
