Author/Authors :
Barbouch, Samia Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Gaied, Hanene Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Ben Abdelghani, Khaoula Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Goucha, Rim Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Lakhal, Amel Hôpital Charles Nicolle - Department of Bone Transplantation, Tunisia , Torjemen, Lamia Hôpital Charles Nicolle - Department of Bone Transplantation, Tunisia , Ben Hamida, Fethi Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Abderrahim, Ezzedine Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Ben Maiz, Hedi Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Hedri, Hafedh Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia , Adel, Khedher Hôpital Charles Nicolle - Department of Nephrology, Laboratory of Renal Pathology, Tunisia
Abstract :
Disturbed kidney function is a common complication after bone marrow transplantation. Recently,attention has been given to immune-mediated glomerular damage related to graft versus host disease (GVHD). We describe a 19-year-old woman who developed membranous glomerulonephritis after bone marrow transplantation (BMT). Six months later,she developed soft palate,skin and liver lesions considered to be chronic GVHD. Fifteen months after undergoing BMT,this patient presented with nephrotic syndrome. A renal biopsy showed membranous glomerulonephritis associated with a focal segmental glomerulosclerosis. She was started on corticosteroid treatment with good outcome.
