Author/Authors :
Rather, Fayaz A. Sher-I-Kashmir Institute of Medical Sciences - Department of Cardiology, India , Najar, Saleem M. Sher-I-Kashmir Institute of Medical Sciences - Department of Nephrology, India , Malla, Hilal A. Sher-I-Kashmir Institute of Medical Sciences - Department of Nephrology, India , Ahangar, A. G. Sher-i-Kashmir Institute of Medical Sciences - Department of Cardiovascular and Thoracic Surgery, India , Bhat, Hilal M. Sher-I-Kashmir Institute of Medical Sciences - Department of Nephrology, India , Wani, Imtiyaz A. Sher-i-Kashmir Institute of Medical Sciences (SKIMS) - Department of Nephrology, India
Abstract :
Our objective is to determine the incidence,etiology,risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence,etiology and outcome. Post-operative AKI was considered when the post-operative serum creatinine was 1.5 mg/dL or there was doubling of serum creatinine above the baseline (pre-operative) with a prior normal renal function. The incidence of AKI in the post-operative period in our study was 17.7%. The common etiological factors for AKI in our study were sepsis, hypotension, prolonged need for ventilator and inotropic support and drugs given in the post-operative period. The important risk factors for the development of AKI in the post-operative period were hypertension,diabetes mellitus,gout,prolonged total bypass time and prolonged aortic cross-clamp time. The overall mortality in our study subjects was 11.3% (seven of 62 died) and the mortality in the patients who developed post-operative AKI was 71.4%.
