Screening of Different Parts of Jatropha Curcas for Antinociceptive and Antipyretic Activity on Rats

Jatropha curcas is an ornamental, medicinal and multipurpose shrub belonging to the family Euphorbiaceae. Different parts of Jatropha have been used traditionally to cure various diseases like fever, rheumatism, jaundice and bacterial infection. In this present work alcoholic extracts of leaves, stems and roots of J. curcas (200 mg/kg) were evaluated for its antinociceptive and antipyretic activity in rats. The alcoholic extracts of stems and roots showed significant analgesic activity and they also produced significant reduction in yeast induced pyrexia. The alcoholic extract of roots exhibited analgesic activity without alteration in peak effect and significant reduction in pyrexia that was comparable to standard drugs pantazocine and paracetamol respectively