Cleft Lip / Palate and Genetics

CLP has a multifactorial etiology, comprising both genetic and environmental factors. They are congenital abnormalities which carry not only medical, but also psychological, social and economical concerns. The determination of the etiologies of cleft lip and palate is extremely important in order to improve their treatment procedures and protective approaches. Genetics is one of the most effective causes of many congenital anomalies. The genetic background of cleft lip and palate will be described in detail in this review article.